Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pou5f1  POU domain, class 5, transcription factor 1   (Synonyms: Oct-3, Oct-3/4, Oct3/4, Oct4, Oct-4, Otf3, Otf-3, Otf3g, Otf3-rs7, Otf4, Otf-4)
Results	Reference
1	J:81247 Beck S, Le Good JA, Guzman M, Ben Haim N, Roy K, Beermann F, Constam DB, Extraembryonic proteases regulate Nodal signalling during gastrulation. Nat Cell Biol. 2002 Dec;4(12):981-5
1*	J:264256 Bernardo AS, Jouneau A, Marks H, Kensche P, Kobolak J, Freude K, Hall V, Feher A, Polgar Z, Sartori C, Bock I, Louet C, Faial T, Kerstens HHD, Bouissou C, Parsonage G, Mashayekhi K, Smith JC, Lazzari G, Hyttel P, Stunnenberg HG, Huynen M, Pedersen RA, Dinnyes A, Mammalian embryo comparison identifies novel pluripotency genes associated with the naive or primed state. Biol Open. 2018 Aug 17;7(8):bio033282
1	J:70006 Brennan J, Lu CC, Norris DP, Rodriguez TA, Beddington RS, Robertson EJ, Nodal signalling in the epiblast patterns the early mouse embryo. Nature. 2001 Jun 21;411(6840):965-9
1	J:92066 Chu GC, Dunn NR, Anderson DC, Oxburgh L, Robertson EJ, Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo. Development. 2004 Aug;131(15):3501-12
1	J:160475 Chu J, Shen MM, Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis. Dev Biol. 2010 Jun 1;342(1):63-73
1	J:249198 Claveria C, Giovinazzo G, Sierra R, Torres M, Myc-driven endogenous cell competition in the early mammalian embryo. Nature. 2013 Aug 1;500(7460):39-44
1	J:154783 Costello I, Biondi CA, Taylor JM, Bikoff EK, Robertson EJ, Smad4-dependent pathways control basement membrane deposition and endodermal cell migration at early stages of mouse development. BMC Dev Biol. 2009;9:54
1	J:239417 Dai HQ, Wang BA, Yang L, Chen JJ, Zhu GC, Sun ML, Ge H, Wang R, Chapman DL, Tang F, Sun X, Xu GL, TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling. Nature. 2016 Oct 27;538(7626):528-532
1	J:124681 Di-Gregorio A, Sancho M, Stuckey DW, Crompton LA, Godwin J, Mishina Y, Rodriguez TA, BMP signalling inhibits premature neural differentiation in the mouse embryo. Development. 2007 Sep;134(18):3359-69
1	J:98382 Donnison M, Beaton A, Davey HW, Broadhurst R, L'huillier P, Pfeffer PL, Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development. 2005 May;132(10):2299-308
1	J:218169 Donnison M, Broadhurst R, Pfeffer PL, Elf5 and Ets2 maintain the mouse extraembryonic ectoderm in a dosage dependent synergistic manner. Dev Biol. 2015 Jan 1;397(1):77-88
1	J:154368 Farkas DR, Chapman DL, Kinked tail mutation results in notochord defects in heterozygotes and distal visceral endoderm defects in homozygotes. Dev Dyn. 2009 Oct 29;238(12):3237-3247
1*	J:71786 Fuhrmann G, Chung AC, Jackson KJ, Hummelke G, Baniahmad A, Sutter J, Sylvester I, Scholer HR, Cooney AJ, Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell. 2001 Sep;1(3):377-87
1*	J:97625 Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, Price RR, Galardi C, Peng L, Latour AM, Koller BH, Gossen J, Kliewer SA, Cooney AJ, Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development. Mol Cell Biol. 2005 May;25(9):3492-505
1*	J:217689 Guzman-Ayala M, Sachs M, Koh FM, Onodera C, Bulut-Karslioglu A, Lin CJ, Wong P, Nitta R, Song JS, Ramalho-Santos M, Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast. Development. 2015 Jan 1;142(1):118-27
1	J:79491 Hanna LA, Foreman RK, Tarasenko IA, Kessler DS, Labosky PA, Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 2002 Oct 15;16(20):2650-61
1*	J:295945 Kawamura N, Takaoka K, Hamada H, Hadjantonakis AK, Sun-Wada GH, Wada Y, Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. Cell Rep. 2020 Jun 9;31(10):107733
1*	J:70278 Kimura C, Shen MM, Takeda N, Aizawa S, Matsuo I, Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast. Dev Biol. 2001 Jul 1;235(1):12-32
1	J:324183 Kimura-Yoshida C, Mochida K, Kanno SI, Matsuo I, USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components. Commun Biol. 2022 Apr 19;5(1):378
1*	J:204971 Li L, Liu C, Biechele S, Zhu Q, Song L, Lanner F, Jing N, Rossant J, Location of transient ectodermal progenitor potential in mouse development. Development. 2013 Nov;140(22):4533-43
1*	J:98254 Okita K, Kiyonari H, Nobuhisa I, Kimura N, Aizawa S, Taga T, Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development. Genes Cells. 2004 Nov;9(11):1083-91
1	J:88053 Perea-Gomez A, Camus A, Moreau A, Grieve K, Moneron G, Dubois A, Cibert C, Collignon J, Initiation of gastrulation in the mouse embryo is preceded by an apparent shift in the orientation of the anterior-posterior axis. Curr Biol. 2004 Feb 3;14(3):197-207
1	J:85863 Robertson EJ, Norris DP, Brennan J, Bikoff EK, Control of early anterior-posterior patterning in the mouse embryo by TGF-beta signalling. Philos Trans R Soc Lond B Biol Sci. 2003 Aug 29;358(1436):1351-7; discussion 1357
1	J:85868 Saba-El-Leil MK, Vella FD, Vernay B, Voisin L, Chen L, Labrecque N, Ang SL, Meloche S, An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep. 2003 Oct;4(10):964-8
1*	J:235456 Song L, Chen J, Peng G, Tang K, Jing N, Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Response to Extrinsic Bone Morphogenetic Protein (BMP) Signaling. J Biol Chem. 2016 Jul 15;291(29):15212-25
1	J:239945 Souilhol C, Perea-Gomez A, Camus A, Beck-Cormier S, Vandormael-Pournin S, Escande M, Collignon J, Cohen-Tannoudji M, NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo. Development. 2015 Nov 01;142(21):3649-60
1	J:163670 Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA, An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. Dev Cell. 2010 Aug 17;19(2):207-19
1	J:272362 Su X, Wu C, Ye X, Zeng M, Zhang Z, Che Y, Zhang Y, Liu L, Lin Y, Yang R, Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development. Cell Death Dis. 2018 Feb 21;9(3):302
1*	J:138922 Uez N, Lickert H, Kohlhase J, de Angelis MH, Kuhn R, Wurst W, Floss T, Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo. Genesis. 2008 Sep 9;46(9):463-477
1	J:146397 Wanderling S, Simen BB, Ostrovsky O, Ahmed NT, Vogen SM, Gidalevitz T, Argon Y, GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. Mol Biol Cell. 2007 Oct;18(10):3764-75
1	J:138862 Warr N, Powles-Glover N, Chappell A, Robson J, Norris D, Arkell RM, Zic2-associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation. Hum Mol Genet. 2008 Oct 1;17(19):2986-96
1*	J:187950 Western P, Maldonado-Saldivia J, van den Bergen J, Hajkova P, Saitou M, Barton S, Surani MA, Analysis of Esg1 expression in pluripotent cells and the germline reveals similarities with Oct4 and Sox2 and differences between human pluripotent cell lines. Stem Cells. 2005 Nov-Dec;23(10):1436-42
1	J:146156 Yamamoto M, Beppu H, Takaoka K, Meno C, Li E, Miyazono K, Hamada H, Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo. J Cell Biol. 2009 Jan 26;184(2):323-34